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The signals produced by the sensors' responses to the calibrant solution are measured. During the first part of the testing cycle, the calibrant solution is released from its foil pack and is positioned over the sensors. Calibration is performed each time a cartridge requiring calibration is used, automatically.
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What analytes on the i-STAT 1 system are measured and which are calculated? Measured: Hematocrit (Hct), Blood Urea Nitrogen (BUN), Creatinine (Crea), Ionized Calcium (iCa), Glucose (Glu), Chloride (Cl), Sodium (Na), Potassium (K), pH, Partial pressure of carbon dioxide (PCO2), Partial pressure of oxygen (PO2), Lactate, Activated Clotting time with Celite® activator (ACT), Cardiac Troponin I (cTnI) Calculated: Hemoglobin (Hb), Bicarbonate (HCO3), Total carbon dioxide concentration (TCO2), Oxygen saturation (sO2), Anion gap (AnGap), Base Excess (BE)ĭoes the i-STAT 1 require calibration? No. These ranges are available in the user guide provided with the analyzer. What species does the i-STAT 1 have reference ranges for? Cat, dog, and horse. What is the shelf-life of the i-STAT 1 cartridges? The cartridges are manufactured with 5-11 months shelf life, depending on the stability of the analytes in each cartridge. What type of sample is used? Whole blood. These cartridges are configured with parameters that can give a clear patient's condition depending on the clinical situation. What kinds of tests can be run on the i-STAT 1 instrument? The i-STAT 1 offers a variety of disposable, single-use cartridges (10) including tests for acid/base analysis, blood gases, chemistry, hematology, electrolytes, and some specialty tests like Lactate, ACT, and Cardiac Troponin I. This difference in signal is then converted to the specific concentration units for the analyte using the analyzer's internal processor. The concentration of the analyte is determined by measuring the difference in signal from the calibrant and the sample. The sensors are either potentiometric, measuring changes in the electric potential, amperometric, measuring changes in electric current, or conductometric measuring changes in conductivity. These coated sensors react to small changes caused by chemical reactions in the sample. A group of thin film electrodes located at the top of a cartridge are coated with chemically sensitive films. Measurement is accomplished using electrochemical sensing technologies.
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What technology does the i-STAT 1 utilize? Electrochemistry.